Cancer BiologybioRxiv
Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes
S. Monterisi, J. Michl, A. E. Hill…·P. Swietach
The paper shows that gap junction-mediated metabolite exchange rescues functional defects caused by inactivating mutations in metabolite-handling genes in colorectal cancer cells.
DOI 10.7554/elife.78425