Author

W. Fujibuchi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. Yamane· 3 shared H. Sone· 2 shared J. K. Yamashita· 2 shared K. Kobayashi· 2 shared A. Hotta· 1 shared H. Kouzuki· 1 shared H. Otsuki· 1 shared H. Xu· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersPharmacology & Toxicology

J. Yamane

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3 papers

Recent·Most cited

AMPK-p38 axis converts human pluripotent stem cells to naïve state

Y. Zhennan, Y. Liu, H. Xu, J. Yamane, A. Hotta, W. Fujibuchi, J. K. Yamashita

This paper identifies the AMPK-p38 signaling axis as a pathway to convert primed human pluripotent stem cells to the naive state using AICAR or CA-p38.

bioRxiv · Mar 31, 2022Cell Biology

Prediction of broad chemical toxicities using induced pluripotent stem cells and gene networks by transfer learning from embryonic stem cell data

J. Yamane, T. Wada, H. Otsuki, K. Inomata, M. Suzuki, T. Hisaki, S. Sekine, H. Kouzuki, K. Kobayashi, H. Sone, J. K. Yamashita, M. Osawa, M. K. Saito, W. Fujibuchi

This paper predicts chemical toxicities using induced pluripotent stem cells and gene networks via transfer learning from embryonic stem cell data, achieving high accuracy across multiple toxicity categories.

bioRxiv · Nov 5, 2021 · PreprintPharmacology & Toxicology

Human ES and iPS Cells Display Less Drug Resistance Than Differentiated Cells, and Naïve-State Induction Further Decreases Drug Resistance

Y. Panina, J. Yamane, K. Kobayashi, H. Sone, W. Fujibuchi

The paper compares drug resistance of human ES and iPS cells with differentiated cells and shows that naive-state induction increases drug sensitivity.

bioRxiv · Aug 17, 2020 · PreprintPharmacology & Toxicology