Author

H. Sone

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

J. Yamane· 2 shared K. Kobayashi· 2 shared W. Fujibuchi· 2 shared A. Oishi· 1 shared H. Iwasaki· 1 shared H. Kouzuki· 1 shared H. Nansai· 1 shared H. Ohno· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersPharmacology & Toxicology

J. Yamane

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Prediction of broad chemical toxicities using induced pluripotent stem cells and gene networks by transfer learning from embryonic stem cell data

J. Yamane, T. Wada, H. Otsuki, K. Inomata, M. Suzuki, T. Hisaki, S. Sekine, H. Kouzuki, K. Kobayashi, H. Sone, J. K. Yamashita, M. Osawa, M. K. Saito, W. Fujibuchi

This paper predicts chemical toxicities using induced pluripotent stem cells and gene networks via transfer learning from embryonic stem cell data, achieving high accuracy across multiple toxicity categories.

bioRxiv · Nov 5, 2021 · PreprintPharmacology & Toxicology

Human ES and iPS Cells Display Less Drug Resistance Than Differentiated Cells, and Naïve-State Induction Further Decreases Drug Resistance

Y. Panina, J. Yamane, K. Kobayashi, H. Sone, W. Fujibuchi

The paper compares drug resistance of human ES and iPS cells with differentiated cells and shows that naive-state induction increases drug sensitivity.

bioRxiv · Aug 17, 2020 · PreprintPharmacology & Toxicology

Enterohepatic transcription factor CREB3L3 protects atherosclerosis via SREBP competitive inhibition

H. Shimano, Y. Nakagawa, Y. Yunong Wang, S.-i. Han, K. Okuda, A. Oishi, Y. Yagishita, K. Kumagai, H. Ohno, Y. Osaki, Y. Mizunoe, Y. Murayama, H. Iwasaki, M. Konishi, N. Itoh, , M. Araki

This study shows CREB3L3 protects against atherosclerosis by inhibiting SREBP activity through competitive antagonism, reducing lipogenic and cholesterogenic gene expression.

bioRxiv · Apr 29, 2020Physiology

Epigenetic Effects of Exposure to Insecticide on Early Differentiation of Mouse Embryonic Stem Cells

W. Wang, S. Otsuka, H. Nansai, T. Ito, K. Abe, Y. Nakao, J. Ohgane, M. Yoneda, H. Sone

This study evaluates the effects of insecticides on DNA methylation during early mouse embryonic stem cell differentiation and identifies imidacloprid's potential developmental impact through altered methylation patterns.

bioRxiv · May 5, 2019Pharmacology & Toxicology