Author

W. Jang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

N. A. Lambert· 3 shared S. Lu· 3 shared A. Inoue· 1 shared D. Kim· 1 shared D.-K. Kim· 1 shared D.-S. Lim· 1 shared G. Feinberg· 1 shared J. Kim· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersPharmacology & Toxicology

N. A. Lambert

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Visualization of endogenous G proteins on endosomes and other organelles

W. Jang, K. Senarath, G. Feinberg, S. Lu, N. A. Lambert

The paper visualizes endogenous G proteins on endosomes and other organelles using gene editing and microscopy, showing their distribution and trafficking.

bioRxiv · Mar 5, 2024Pharmacology & Toxicology

Formation of a giant unilocular vacuole via macropinocytosis-like process confers anoikis resistance

J. Kim, D. Kim, D.-K. Kim, S.-H. Lee, W. Jang, D.-S. Lim

The paper shows that disrupting the actin cytoskeleton leads to the formation of a giant unilocular vacuole, which confers anoikis resistance in cells losing matrix attachment.

bioRxiv · Jan 31, 2024Cell Biology

Nucleotide-decoupled G proteins reveal the role of G protein conformation in receptor-G protein selectivity

W. Jang, S. Lu, N. A. Lambert

This study investigates GPCR-G protein selectivity by using nucleotide-decoupled G protein variants, finding that selectivity decreases when nucleotide release is not required for complex formation.

bioRxiv · May 25, 2022Pharmacology & Toxicology

Constitutive G protein coupling profiles of understudied orphan GPCRs

S. Lu, W. Jang, A. Inoue, N. A. Lambert

The paper uses BRET to determine G protein coupling profiles of 48 orphan GPCRs without ligands, identifying 48 receptor-G protein pairs, many previously unknown.

bioRxiv · Feb 16, 2021Pharmacology & Toxicology