Author

W. Peppel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

H. Durden· 3 shared R. Gallegos· 3 shared S. Saffarian· 3 shared A. Petersen· 2 shared B. MacArthur· 2 shared B. Preece· 2 shared I. Saha· 2 shared A. Ivanova· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCell Biology

H. Durden

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Kinetic landscape of single virus-like particles highlights the efficacy of SARS-Cov-2 internalization

A. S. Atemin, A. Ivanova, W. Peppel, R. Stamatov, R. Gallegos, H. Durden, S. Uzunova, M. Vershinin, S. Saffarian, S. Stoynov

This study measures the kinetics of SARS-CoV-2 virus-like particle internalization using live-cell microscopy, revealing key steps and their timing, and showing no effect of Omicron mutations or S protein cleavage site on internalization rates.

bioRxiv · Jun 10, 2024Cell Biology

Competitive assembly resolves the stoichiometry of essential proteins in infectious HIV-1 virions.

H. Durden, B. Preece, R. Gallegos, I. Saha, B. MacArthur, A. Petersen, W. Peppel, S. Saffarian

The paper measures the stoichiometry of Gag-Pol and gp120/gp41 proteins in infectious HIV-1 virions using a competitive assembly method, finding it similar to all released virions.

bioRxiv · Mar 10, 2024 · PreprintBiophysics

Competitive HIV budding suggests that a self-packaging gRNA:Gag-Pol complex directs HIV assembly and enforces infectivity.

H. Durden, I. Saha, B. Preece, B. MacArthur, A. Petersen, W. Peppel, R. Gallegos, S. Saffarian

The paper investigates HIV assembly by testing infectious/non-infectious genome mixtures, finding that a gRNA:Gag-Pol complex drives virion formation and infectivity.

bioRxiv · Aug 3, 2022 · PreprintMicrobiology