Animal Behavior & CognitionbioRxiv
Early Detection of Apathetic Phenotypes in Huntington’s Disease Knock-in Mice Using Open Source Tools
S. Minnig, R. M. Bragg, H. S. Tiwana…·J. B. Carroll
The paper develops an open-source operant system to detect apathetic phenotypes in Huntington’s disease mice, finding reduced progressive ratio task performance in HttQ111/+ mice at 9-11 months.
DOI 10.1038/s41598-018-20607-7