MicrobiologybioRxiv
Type III-A CRISPR systems as a versatile gene knockdown technology
W. T. Woodside, N. Vantsev, M. P. Terns
This study demonstrates the use of type III-A CRISPR-Cas systems for efficient and specific gene knockdown in E. coli by designing tailored CRISPR RNAs to target both coding and non-coding RNAs.
DOI 10.1261/rna.079206.122