Author

Wade C. Barton

University of Alabama

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Biochemistry· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

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Alex S ChoiiD· 1 shared Andrew B. NixoniD· 1 shared Asha KumariiD· 1 shared Calen Raulerson· 1 shared Carly L. LancasteriD· 1 shared Diego AltomareiD· 1 shared Hao JiiD· 1 shared Karthikeyan MythreyeiD· 1 shared

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alex S ChoiORCID

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1 paper

Recent·Most cited

BiochemistryCell Communication and SignalingPeer-reviewedFeb 15, 2024

Heparan sulfate modifications of betaglycan promote TIMP3-dependent ectodomain shedding to fine-tune TGF-β signaling.

Alex S Choi, Laura M. Jenkins, Wade C. Barton…·Karthikeyan Mythreye

This study identifies heparan sulfate modifications as critical for betaglycan ectodomain shedding, which regulates TGF-β signaling and has clinical implications in ovarian cancer.

7 citations

humanexperimental assay

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