Author

Weinan Zhang

University of Missouri

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Biology Disciplines

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Bioinformatics· 1

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

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Chaohan LiiD· 1 shared Dong XuiD· 1 shared Duolin WangiD· 1 shared Qing ShaoiD· 1 shared Shuai ZengiD· 1 shared Yuexu Jiang· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperBioinformatics

Chaohan LiORCID

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1 paper

Recent·Most cited

BioinformaticsBiophysical JournalPeer-reviewedFeb 4, 2026

ProtLoc-GRPO: Cell line-specific subcellular localization prediction using a graph-based model and reinforcement learning

Shuai Zeng, Weinan Zhang, Chaohan Li…·Dong Xu

This study introduces ProtLoc-GRPO, a reinforcement learning method that improves subcellular localization prediction by optimizing PPI networks, achieving a 7% macro-F1 score improvement.

DOI 10.1016/j.bpj.2026.02.001

protein sequencedeep learning

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