Cell BiologybioRxivPreprint
Inhibition of GEF-H1-RhoA signaling in inflammation with a stapled peptide mimicry of the RhoA67-78 helix
Clara Gathmann, Tiansheng Liu, Shuhuai Yang…·David L. Selwood
The paper designs a stapled peptide stP5 that inhibits GEF-H1-RhoA signaling in inflammation, showing 100-fold higher activity than the unstapled P5 peptide.
DOI 10.1101/2024.11.18.624118