Systems BiologybioRxivPreprint
Analysis of the phosphorylation networks characterizing distinct phenotypic states in glioblastoma cell Populations
Januka Khanal, Chunxiao Ren, Wenue Li…·Andre Levchenko
The paper identifies phenotype-specific signaling networks in glioblastoma cells, showing that invasive spread is linked to DNA damage response and AKT-mTOR activation, with 14-3-3 proteins mediating phosphorylation and predictive phospho-site signatures for patient survival.
DOI 10.1101/2025.08.22.671611