Author

William Reagan Kesting

Icahn School of Medicine at Mount Sinai

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Biology Disciplines

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Genetic & Genomic Medicine· 1

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Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Approach:statistical model· 1

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Alanna C. CoteiD· 1 shared Judit García‐GonzáleziD· 1 shared Paul F. O’ReillyiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Alanna C. CoteORCID

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1 paper

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintSep 7, 2026

Modeling pathway overlap increases accuracy of GWAS gene set enrichment

Alanna C. Cote, William Reagan Kesting, Judit García‐González, Paul F. O’Reilly

This paper introduces GSR, a method to adjust for pathway overlap in GWAS gene set enrichment, improving the accuracy of identifying biologically relevant pathways.

DOI 10.64898/2026.09.03.26362206

GWAS summary statisticsstatistical model

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