NeuroscienceMolecular NeurodegenerationPeer-reviewed
Elevated nuclear TDP-43 induces constitutive exon skipping
Rogger P. Carmen‐Orozco, William Tsao, Yingzhi Ye…·Jonathan P. Ling
This study shows that elevated nuclear TDP-43 causes species-specific exon skipping, which differs from exon skipping seen in TDP-43 loss-of-function, highlighting the need for careful interpretation of TDP-43 overexpression models.