NeuroscienceBiological Psychiatry Global Open SciencePeer-reviewed
Modeling intrahippocampal effects of anterior hippocampal hyperactivity relevant to schizophrenia using chemogenetic excitation of long axis-projecting mossy cells in the mouse dentate gyrus
James P. Bauer, Sarah L. Rader, Max E. Joffe…·Alan S. Lewis
This study shows that hyperactivating ventral dentate gyrus mossy cells impairs spatial memory in mice, suggesting intrahippocampal hyperactivity may contribute to schizophrenia-related cognitive deficits.
15 citations