BiophysicsbioRxiv
Structural mechanism underpinning Thermus oshimai Pif1-mediated G-quadruplex unfolding
D. Yang-Xue, G. Hai-Lei, L. Na-Nv…·X. XUGUANG
This study presents the first X-ray structure of Thermus oshimai Pif1 bound to a G-quadruplex, revealing how it recognizes and unfolds G4s through a distinct mechanism compared to DHX36.
DOI 10.15252/embr.202153874