Effect of Total Sphingomyelin Synthase Activity on Low Density Lipoprotein Catabolism in Mice
X.-C. Jiang, Z. Li, M. He, T. S. Worgall, G. Chen
This study shows that total sphingomyelin synthase (SMS) deficiency reduces LDL receptors and impairs LDL catabolism in mice, while SMS2 deficiency does not have this effect.
bioRxiv · Feb 3, 2023 · PreprintBiochemistry