Author

Xia Chen

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

Click to filter author papers

Pharmacology & Toxicology· 2 Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Assay:proteomics· 2 Organism:rat· 2 Approach:statistical model· 2

Frequent Co-Authors

Abigail Plone· 1 shared Adam R. Greene· 1 shared Aneeta Hotwani· 1 shared Ashish JainiD· 1 shared Asra Usmani· 1 shared Casey R. Johnson· 1 shared Changming Wang· 1 shared Chelsea Asare· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperDevelopmental Biology

Abigail Plone

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Screening and evaluation of medicine food homology herbal combinations for ameliorating chemotherapy induced ovarian aging under an integrated multi-strategy framework

jinmei Zhang, Xia Chen, Yahui Cao, Yaou Liu, Nan Ning, Weijie Bian, Xiangning Yang, Yanlei Guo, Jin Zeng

This paper identifies Astragalus ginseng as a candidate herb pair for ameliorating chemotherapy-induced ovarian aging using a multi-strategy framework combining single-cell transcriptomics, chemical profiling, and molecular modeling.

bioRxiv · Oct 28, 2026 · PreprintPharmacology & Toxicology

1,3- and 1,4-linked Polysaccharides Uptake in Intestinal Cells Relies on Clathrin/Dynamin 1/Rab5-dependent Endocytosis

Wenfeng Liao, Dianxiu Cao, Ying Wang, Zhenyun Du, Yao Jx, Pengfei Dou, Yuandong Zheng, Zhiming Wang, Xia Chen, Peipei Wang, Chungwah Ma, Hao Chen, Xingxing Diao, Kaiping Wang, Kan Ding

Orally administered β-1,3- and α-1,4-linked polysaccharides cross intestinal epithelium into rodent plasma and liver as macromolecules via clathrin-, dynamin 1-, and Rab5-dependent endocytosis mediated by EGFR, Dectin-1, and BMPRIA.

Nature Communications · Jan 26, 2026Peer-reviewedPharmacology & Toxicology✦ In-depth digest

Development of the Early Childhood Duodenum across Ancestry, Geography and Environment

Joshua de Sousa Casal, Krishnan Raghunathan, Chelsea Asare, Abigail Plone, Nazanin Moradinasab, Junaid Iqbal, Lianna Wood, Elsy M. Ngwa, Xia Chen, S. Fisher Rhoads, Clara Baek, Dur-e Shahwar, Neha S. Dhaliwal, Madison Wong, Max Garrity-Janger, , Jay R. Thiagarajah

The paper creates a cellular and spatial map of the duodenum in children, revealing environmental and developmental influences on intestinal cell states.

bioRxiv · Dec 17, 2025 · PreprintDevelopmental Biology

Lipid Droplets of Human Carotid Atherosclerotic Plaques: Cholesteryl Arachidonate Core and Cytoskeletal Fibrotic Cover

Yilu Xu, Yang Wang, Guangxin Yang, Qichen Feng, Xiaochuan Fu, Qiumin Liao, Xiao-Juan Wei, Xia Chen, Hongchao Zhang, Shuyan Zhang, Changming Wang, Pingsheng Liu

This study characterizes lipid droplets in human atherosclerotic plaques, revealing their unique lipid and protein composition, including high levels of inflammatory precursors and cytoskeletal proteins.

bioRxiv · Aug 18, 2025 · PreprintCell Biology