Xianbang Sun

This paper introduces a clustering method to identify causal rare variants and classify their effect directions using summary statistics from gene-based tests.

The paper examines heteroplasmic mitochondrial genetic variants in human cardiac tissues and finds they differ from those in blood and skeletal muscle, with higher variant counts in cardiac tissue linked to age.

The paper examines the concordance and characteristics of mitochondrial heteroplasmic mutations in maternal pairs of European and African ancestry, finding higher concordance in close relatives and associations with age and nuclear genome regions.

This study identifies 20 alcohol-associated proteins and shows complex relationships between alcohol consumption, circulating proteins, and cardiovascular disease risk factors.