BioinformaticsbioRxivPreprint
Multimodal AI for Single cfDNA Profiling and Cancer Screening
Bo Wang, Liyang Song, Hefei Li…·Yingjiang Ye
The paper develops a Transformer-based model called cfAI to profile and detect cancer-derived cfDNA by integrating methylation, fragmentomics, and histone modifications, achieving high sensitivity and specificity in multi-cancer detection.
DOI 10.64898/2025.12.29.696856