NeurosciencebioRxivPreprint
Suboptimal phenotypic reliability impedes reproducible human neuroscience
Aki Nikolaidis, Andrew A. Chen, Xiaoning He…·Haochang Shou
Simulations and neuroimaging analyses argue that unreliable clinical and cognitive phenotypes, not only noisy fMRI, cap biomarker discovery; aggregating across raters or repeated measures beats enlarging samples.