PhysiologybioRxivPreprint
Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction
Martin Wohlwend, Pirkka-Pekka Laurila, Ludger J.E. Goeminne…·Johan Auwerx
This study shows that reducing CERS1 in skeletal muscle worsens age-related muscle dysfunction in mice and humans, linking it to inflammation and fibrosis.