Xingyan Wang

The paper develops an in-silico cell sorting method to identify granulocyte-specific gene expression biomarkers from bulk blood data, enabling discrimination between bacterial and viral infections.

The paper introduces RACE, a method for rapidly evolving NRPSs through recombineering, generating novel peptides and uncovering new recombination sites.

This paper introduces a strategy to activate silent NRPS biosynthetic gene clusters by swapping initiation units, successfully recovering three of six previously silent pathways and identifying five novel lipopeptides.

This paper develops a ratio-based biomarker (DIRECT LS-TA) using monocyte-specific gene expression ratios in peripheral blood to improve viral infection triage, outperforming the IFN score in diagnostic accuracy.