Systems BiologyBiophysical JournalPeer-reviewed
Dynamic mechanisms of time-of-day-dependent adaptive immunity and vaccination responses
Xinyang Weng, Qi Ouyang, Hongli Wang
This paper uses mathematical modeling to show that bistability in dendritic cell homing, regulated by the circadian clock, explains time-of-day-dependent immune responses to vaccines.
DOI 10.1016/j.bpj.2026.01.041