BioinformaticsThe Annals of Applied StatisticsPeer-reviewed
A Compositional Model To Assess Expression Changes From Single-Cell RNA-Seq Data
Xiuyu Ma, Keegan D. Korthauer, Christina M. Kendziorski, Michael A. Newton
The paper introduces an empirical Bayesian mixture model to detect distributional expression changes in single-cell RNA-seq data, showing improved sensitivity over standard approaches.
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