ImmunologyeLifePeer-reviewed
Fish CDK2 recruits Dtx4 to degrade TBK1 through ubiquitination in the antiviral response
Long-Feng Lu, Can Zhang, Zhuo-Cong Li…·Shun Li
This study shows that fish CDK2 recruits Dtx4 to ubiquitinate and degrade TBK1, reducing IFN expression and enhancing antiviral resistance.
2 citations