Author

Xuan Li

Chengdu University of Traditional Chinese Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

Click to filter author papers

Microbiology· 2 Neuroscience· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1

Frequent Co-Authors

Aiswarya SaravananiD· 1 shared Alexei VerkhratskyiD· 1 shared Amrita Kondur· 1 shared Aya SatoiD· 1 shared Beáta SperlághiD· 1 shared Carlos Mario Rodriguez-RezaiD· 1 shared chen Xiao Yang· 1 shared cheng Tian Fan· 1 shared

Activity by Year

2024-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperNeuroscience

Aiswarya SaravananORCID

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

PGG Enhances Olaparib Efficacy via cGAS-STING Signaling and Sensitizes Triple-Negative Breast Cancer to PD- L1 Blockade

han Si Liu, Xuan Li, chen Xiao Yang, ling Mei xiao, cheng Tian Fan, Jie Yu, Jie Zeng

This study shows PGG enhances olaparib efficacy in TNBC by inducing HRD and activates cGAS-STING to sensitize tumors to PD-L1 blockade, converting 'cold' to 'hot' tumors.

bioRxiv · Sep 28, 2026 · PreprintBiochemistry

Multifaceted and evolutionarily dynamic interactions between Caenorhabditis elegans SPO-11 and its cofactors ensure proper formation of meiotic DNA double-strand breaks

Keita Kameda, Li Zhou, Nowa Matsubayashi, Carlos Mario Rodriguez-Reza, Meng Lin, Xuan Li, Tomoki Yoshioka, Aya Sato, Peter Mark Carlton

This paper investigates how SPO-11 and its cofactors, particularly DSB-1, regulate meiotic DNA double-strand break formation in C. elegans through dimerization and evolutionary adaptation.

bioRxiv · Aug 2, 2026 · PreprintCell Biology

P2X7 receptor-mediated astrocytic atrophy in the hippocampus of mice after status epilepticus

Xuan Li, Muhammad Tahir Khan, Elek Sylvester Vizi, Beáta Sperlágh, Si-Si Lin, Alexei Verkhratsky, Patrizia Rubini, Yong Tang, Péter Illés

This study investigates the role of P2X7 receptors in astrocytic atrophy following status epilepticus in mice, showing that P2X7R antagonism prevents astrocyte damage.

bioRxiv · Apr 20, 2026 · PreprintNeuroscience

Delayed forebrain excitatory and inhibitory neurogenesis inSTRADA-related megalencephaly via mTOR hyperactivity

Tong Pan, Grace Lin, Xuan Li, Debora VanHeyningen, J. Clayton Walker, Sahej Kohli, Aiswarya Saravanan, Amrita Kondur, Daniel C. Jaklic, Saul Pantoja-Gutierrez, Shivanshi Vaid, Julie S. Sturza, Ken Inoki, Tomozumi Imamichi, Weizhong Chang, Louis T. Dang

This study shows that mTOR hyperactivity in STRADA-deficient brain organoids causes delayed neurogenesis and altered interneuron fate, which can be rescued by rapamycin.

Stem Cell Reports · Mar 5, 2026Peer-reviewedNeuroscience

Cyclical transcription factor AP2XII-9 is a key activator for asexual division and apicoplast inheritance in Toxoplasma gondii tachyzoite

Yuehong Shi, Xuan Li, Yingying Xue, Dandan Hu, Xingju Song

This study identifies TgAP2XII-9 as a critical S/M-phase transcription factor regulating endodyogeny and apicoplast inheritance in Toxoplasma gondii tachyzoites.

mBio · Aug 29, 2024Peer-reviewedMicrobiology

Coxsackievirus group B3 regulates ASS1-mediated metabolic reprogramming and promotes macrophage inflammatory polarization in viral myocarditis

Qiong Liu, Yinpan Shang, Ziwei Tao, Xuan Li, Lu Shen, Hanchi Zhang, Zhili Liu, Zhirong Rao, Xiaomin Yu, Yanli Cao, Lingbing Zeng, Xiaotian Huang

This study shows CVB3 infection upregulates ASS1 through citrulline consumption, leading to metabolic reprogramming and macrophage inflammatory polarization, contributing to viral myocarditis.

Journal of Virology · Aug 28, 2024Peer-reviewedMicrobiology