Author
University of Michigan
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Tong Pan, Grace Lin, Xuan Li…·Louis T. Dang
This study shows that mTOR hyperactivity in STRADA-deficient brain organoids causes delayed neurogenesis and altered interneuron fate, which can be rescued by rapamycin.
Andrew M. Tidball, Jinghui Luo, J. Clayton Walker…·Jack M. Parent
The paper uses a CRISPRi screen in human iNeurons to identify novel FCD genes that increase mTOR signaling, finding two genes mutated in FCD patient tissue.
Taylor N. Takla, Jinghui Luo, Roksolana Sudyk…·Andrew M. Tidball
This study identifies a shared mechanism of increased lumen size due to reduced apical constriction in brain organoids caused by valproic acid and SHROOM3 knockout.
Andrew M. Tidball, Wei Niu, Qianyi Ma…·Jack M. Parent
The paper describes a method to generate reproducible single-rosette brain organoids from human pluripotent stem cells and uses them to study structural phenotypes in neurodevelopmental disorders.
Andrew M. Tidball, Luis F. Lopez‐Santiago, Yukun Yuan…·Jack M. Parent
This study uses patient-derived iPSC neurons to show variant-specific changes in sodium currents in SCN8A-EIEE13, identifying altered persistent and resurgent INa and potential therapeutic responses.