Cancer BiologybioRxivPreprint
Manufacturing CD20/CD19-targeted iCasp9 regulatable CAR-TSCM cells using qCART, the Quantum pBac-based CAR-T system
P. S. Chang, Y.-C. Chen, W.-K. Hua…·S. C.-Y. Wu
This paper demonstrates the efficient manufacturing of CD20/CD19 dual-targeted, iCasp9-regulatable CAR-TSCM cells using the virus-free qCART system, showing robust tumor eradication and safety.
DOI 10.1101/2022.05.03.490475