Pharmacology & ToxicologybioRxiv
Neuroprotective effects of exogenous erythropoietin in Wistar rats by downregulating apoptotic factors to attenuate N-methyl-D-aspartate-mediated retinal ganglion cells death
W.-S. Cheng, I.-H. Lin, K. M. Feng…·D.-W. Lu
This study shows that exogenous EPO reduces NMDA-induced retinal ganglion cell death in rats by downregulating apoptotic factors like calpain, Bax, and caspase 9.