BiophysicsbioRxiv
Parsing the roles of neck-linker docking and tethered head diffusion in the stepping dynamics of kinesin
Z. Zhang, Y. Goldzvik, D. Thirumalai
This study uses molecular simulations to quantify how neck-linker docking and trailing head diffusion contribute to kinesin's 16 nm step on microtubules, showing diffusion accounts for most of the movement.
DOI 10.1073/pnas.1706014114