Author

Y. Gupta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Nogales· 1 shared A.-P. Lin· 1 shared C. Jaafar· 1 shared D. Morales Vasquez· 1 shared G. Huelgas-Morales· 1 shared J. C. de la Torre· 1 shared J. Khalife· 1 shared K. Chiem· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

A. Nogales

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

IRF8-mutant B cell lymphoma evades immunity through a CD74-dependent deregulation of antigen processing and presentation in MHC CII complexes

Z. Qiu, J. Khalife, A.-P. Lin, P. Ethiraj, C. Jaafar, L. Chiou, G. Huelgas-Morales, S. Aslam, S. Arya, Y. Gupta, P. Dahia, R. Aguiar

This study shows that IRF8 mutations in DLBCL lymphomas impair antigen processing and presentation by reducing CD74 and HLA-DM, leading to immune evasion and increased tumor burden.

bioRxiv · Oct 14, 2023Cancer Biology

Antivirals against monkeypox infections

K. Chiem, A. Nogales, M. M. Lorenzo, D. Morales Vasquez, Y. Xiang, Y. Gupta, R. Blasco, J. C. de la Torre, L. Martinez-Sobrido

This study evaluates 19 compounds for antiviral activity against Orthopoxviruses, identifying 13 with activity against vaccinia virus and 11 with activity against monkeypox virus.

bioRxiv · Apr 19, 2023 · PreprintMicrobiology