TGF-β inhibitor accelerates BMP4-induced cochlear gap junction formation during in vitro differentiation of embryonic stem cells
I. Fukunaga, C. Chen, Y. Oe, K. Danzaki, S. Ohta, A. Koike, A. Fujimoto, K. Ikeda, K. Kamiya
This study shows that the TGF-β inhibitor SB431542 accelerates BMP4-induced gap junction formation in CX26GJCs derived from mouse iPSCs, improving their yield for therapeutic applications.
bioRxiv · Feb 17, 2020Cell Biology