Author

S. Ohta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

K.-i. Noma· 2 shared A. Chmielewska· 1 shared A. Fujimoto· 1 shared A. Koike· 1 shared A. Yoshioka· 1 shared C. Chen· 1 shared C. Y.-L. Chung· 1 shared H. Jimbo· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCancer Biology

K.-i. Noma

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Chemo-senolytic therapeutic potential against angiosarcoma

X. Wang, C. Y.-L. Chung, A. Yoshioka, S. Hashimoto, H. Jimbo, H. Tanizawa, S. Ohta, T. Fukumoto, K.-i. Noma

This study explores combining cisplatin and the senolytic agent ABT-263 to treat angiosarcoma, showing that low-dose cisplatin induces senescence, which is then eliminated by ABT-263, reducing chemotherapy side effects.

bioRxiv · Oct 19, 2023Cancer Biology

Zinc-finger protein 518 plays a crucial role in pericentromeric heterochromatin formation by linking satellite DNA to heterochromatin

S. Ohta, J.-I. Ohzeki, N. Sato, K.-I. Noma, H. Masumoto

This study identifies ZNF518's role in pericentromeric heterochromatin formation by linking satellite DNA to heterochromatin through interactions with CENP-B, HP1, and G9a.

bioRxiv · Sep 15, 2022 · PreprintCell Biology

CCDC86/Cyclon is a novel Ki-67 interacting protein important for cell division

K. Stamatiou, A. Chmielewska, S. Ohta, W. Earnshaw, P. Vagnarelli

This study identifies CCDC86/cyclon as a novel chromosome periphery protein involved in mitosis and presents it as a prognostic marker for neuroblastoma.

bioRxiv · Jul 1, 2022Cell Biology

Cooperation among c-subunits of FoF1-ATP synthase in rotation-coupled proton translocation

N. Mitome, S. Kubo, S. Ohta, H. Takashima, Y. Shigefuji, T. Niina, S. Takada

The paper investigates cooperation among c-subunits in FoF1-ATP synthase by analyzing ATP synthesis and proton pump activities with mutated cE56D subunits, showing decreased activity with increasing mutation separation.

bioRxiv · Mar 25, 2021Biochemistry

TGF-β inhibitor accelerates BMP4-induced cochlear gap junction formation during in vitro differentiation of embryonic stem cells

I. Fukunaga, C. Chen, Y. Oe, K. Danzaki, S. Ohta, A. Koike, A. Fujimoto, K. Ikeda, K. Kamiya

This study shows that the TGF-β inhibitor SB431542 accelerates BMP4-induced gap junction formation in CX26GJCs derived from mouse iPSCs, improving their yield for therapeutic applications.

bioRxiv · Feb 17, 2020Cell Biology