BiochemistrybioRxiv
Shear-Mediated Platelet Microparticles Demonstrate Phenotypic Heterogeneity as to Morphology, Receptor Distribution, and Hemostatic Function
Y. Roka-Moiia, K. R. Ammann, S. Miller-Gutierrez…·M. J. Slepian
This study shows that shear stress generates platelet-derived microparticles (PDMPs) with varied morphology and receptor expression, which both enhance thrombin generation and inhibit platelet aggregation.
DOI 10.3390/ijms24087386