Paroxetine-induced transient apoptosis with delayed neurogenesis induces brain remodeling in developing zebrafish
T. Sato, K. Saito, T. Oyu, K. Yamaguchi, M. Osawa, Y. Shiko, Y. Kawasaki, T. Kurisaki, S. Tsuda, T. Kajihara, M. Nagashima
This study shows that early paroxetine exposure in zebrafish embryos causes transient apoptosis, delayed neurogenesis, and brain remodeling linked to ASD-like social behavior impairments.
bioRxiv · Nov 10, 2023 · PreprintPharmacology & Toxicology