S. Tsuda

A combination of two-enzyme system and enzyme engineering improved the activity of a new PET hydrolase identified from soil bacterial genome

The paper identifies a novel PET hydrolase from soil bacteria, enhances its activity with CALB and protein engineering, achieving 95.5% PET degradation.

Paroxetine-induced transient apoptosis with delayed neurogenesis induces brain remodeling in developing zebrafish

This study shows that early paroxetine exposure in zebrafish embryos causes transient apoptosis, delayed neurogenesis, and brain remodeling linked to ASD-like social behavior impairments.

Uncovering novel endolysins against methicillin-resistant Staphylococcus aureus using microbial single-cell genome sequencing

The paper uses microbial single-cell genome sequencing to discover novel endolysins against methicillin-resistant Staphylococcus aureus, identifying a lead endolysin with effective antimicrobial properties.

Single-cell RNA-seq analysis reveals penaeid shrimp hemocyte subpopulations and cell differentiation process

This study uses single-cell RNA sequencing to identify nine hemocyte subpopulations in shrimp and their differentiation pathways.

Establishment of a novel method for the production of chimeric mouse embryos using oil droplets.

This study introduces a novel droplet-based method for producing chimeric embryos, offering better reproducibility and quantification compared to traditional aggregation and injection methods.

High-throughput screening of high protein producer budding yeast using gel microdrop technology

This paper presents a high-throughput screening method using gel microdrop technology to isolate high protein producer budding yeast clones, improving protein production by five-fold.