Cancer BiologybioRxiv
RORc expressing immune cells negatively regulate tertiary lymphoid structure formation and support their pro-tumorigenic functions
E. Cinnamon, I. Stein, E. Zino…·E. Pikarsky
This study shows RORc-expressing immune cells suppress tertiary lymphoid structure (TLS) formation in liver cancer, leading to pro-tumorigenic TLSs, while their absence results in anti-tumorigenic TLSs.
DOI 10.1016/j.jhep.2024.12.015