Author

Y. Stein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

R. Scherz-Shouval· 4 shared M. Pevsner-Fischer· 3 shared O. Levi-Galibov· 3 shared R. Nevo· 3 shared C. Halperin· 2 shared G. Friedman· 2 shared M. Dadiani· 2 shared S. Mayer· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersCancer Biology

R. Scherz-Shouval

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4 papers

Recent·Most cited

Cancer-associated fibroblasts serve as decoys to suppress NK cell anti-cancer cytotoxicity

A. Ben-Shmuel, Y. Gruper, O. Levi-Galibov, H. Rosenberg-Fogler, G. Carradori, Y. Stein, M. Dadiani, M. Naumova, R. Nevo, D. Morzaev-Sulzbach, G. Yagel, S. Mayer, E. Gal-Yam, R. Scherz-Shouval

The paper shows cancer-associated fibroblasts suppress NK cell cytotoxicity by acting as decoys, leading to poor disease outcomes in breast cancer.

bioRxiv · Nov 23, 2023 · PreprintCancer Biology

A cell circuit approach to dissect fibroblast-macrophage interactions in the tumor microenvironment

S. Mayer, T. Milo, A. Isaacson, C. Halperin, S. Miyara, Y. Stein, M. Pevsner-Fischer, E. Tzahor, U. Alon, R. Scherz-Shouval

The paper uses a cell circuit approach to analyze fibroblast-macrophage interactions in the tumor microenvironment, finding that fibroblasts rely on autocrine growth factors while macrophages depend on external cues.

bioRxiv · Nov 17, 2022 · PreprintCancer Biology

BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking CLU+ CAF expression with HSF1 signaling

L. Shaashua, M. Pevsner-Fischer, G. Friedman, O. Levi-Galibov, S. Nandakumar, R. Nevo, L. E. Brown, W. Zhang, Y. Stein, H. S. Kim, L. Bojmar, W. R. Jarnagin, N. Lecomte, R. Stok, H. Bishara, , R. Scherz-Shouval

This study shows BRCA mutations in pancreatic cancer alter CAF subtypes, specifically increasing CLU+ CAFs, and links this to HSF1 signaling.

bioRxiv · Aug 18, 2021 · PreprintCancer Biology

Cancer-associated fibroblast compositions change with breast cancer progression linking S100A4 and PDPN ratios with clinical outcome

G. Friedman, O. Levi-Galibov, E. David, C. Bornstein, A. Giladi, M. Dadiani, A. Mayo, C. Halperin, M. Pevsner-Fischer, H. Lavon-Pashot, R. Nevo, Y. Stein, H. R. Ali, C. Caldas, E. Nili-Gal-Yam, , R. Scherz-Shouval

The paper tracks changes in cancer-associated fibroblast (CAF) subpopulations during breast cancer progression, linking their ratios to clinical outcomes and BRCA mutations.

Nature Cancer · Jun 29, 2020Peer-reviewedCancer Biology