R. Scherz-Shouval

The paper maps stress response networks in tumor microenvironments, revealing distinct activation patterns of oxidative stress in cancer-associated fibroblasts and pericytes across multiple carcinomas.

This study shows that low EIF4G2 expression in Grade 2 endometrial cancer correlates with poor survival and drug resistance, suggesting it as a potential biomarker.

The paper uses a cell circuit approach to analyze fibroblast-macrophage interactions in the tumor microenvironment, finding that fibroblasts rely on autocrine growth factors while macrophages depend on external cues.

This study shows BRCA mutations in pancreatic cancer alter CAF subtypes, specifically increasing CLU+ CAFs, and links this to HSF1 signaling.

This study shows lung fibroblasts in breast cancer metastases are transcriptionally dynamic and plastic, with stage-specific gene signatures and Myc as a key regulator linked to poor survival.

The paper tracks changes in cancer-associated fibroblast (CAF) subpopulations during breast cancer progression, linking their ratios to clinical outcomes and BRCA mutations.