Author

E. Tzahor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:development & morphogenesis· 4 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell-cell communication· 2

Frequent Co-Authors

A. Aharonov· 2 shared A. Shakked· 2 shared D. Kain· 2 shared J. Bakkers· 2 shared K. B. Umansky· 2 shared S. Miyara· 2 shared A. Baehr· 1 shared A. Isaacson· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCell Biology

A. Aharonov

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A cell circuit approach to dissect fibroblast-macrophage interactions in the tumor microenvironment

S. Mayer, T. Milo, A. Isaacson, C. Halperin, S. Miyara, Y. Stein, M. Pevsner-Fischer, E. Tzahor, U. Alon, R. Scherz-Shouval

The paper uses a cell circuit approach to analyze fibroblast-macrophage interactions in the tumor microenvironment, finding that fibroblasts rely on autocrine growth factors while macrophages depend on external cues.

bioRxiv · Nov 17, 2022 · PreprintCancer Biology

Redifferentiated cardiomyocytes retain residual dedifferentiation signatures and are protected against ischaemic injury

A. Shakked, Z. Petrover, A. Aharonov, M. Ghiringhelli, K.-B. Umansky, P. D. Nguyen, D. Kain, J. Elkahal, Y. Divinsky, S. Miyara, G. Friedlander, A. Savidor, L. Zhang, D. Perez, N. Kastan, , E. Tzahor

This study investigates the redifferentiation process in adult mouse hearts after dedifferentiation, finding residual dedifferentiation signatures and protective effects against ischemic injury.

bioRxiv · Feb 22, 2022 · PreprintCell Biology

Glucocorticoid Receptor ablation promotes cardiac regeneration by hampering cardiomyocyte terminal differentiation

N. Pianca, F. Pontis, M. Chirivi, V. Papa, L. Braga, R. S. Patnala, C. Bongiovanni, M. Mazzeschi, K. B. Umansky, G. Cenacchi, M. Lauriola, M. Giacca, R. Rizzi, E. Tzahor, G. D'Uva

This study shows that glucocorticoid receptor ablation enhances cardiac regeneration by reducing cardiomyocyte terminal differentiation and promoting proliferation after myocardial infarction.

bioRxiv · Jan 15, 2020Cell Biology

Agrin promotes coordinated therapeutic processes leading to improved cardiac repair in pigs

A. Baehr, K. B. Umansky, E. Bassat, K. Klett, V. Jurisch, T. Bozoglu, N. Hornaschewitz, O. Solyanik, D. Kain, B. Ferrero, R. Cohen-Rabi, M. Krane, C. Cyran, O. Soehnlein, K. L. Laugwitz, , E. Tzahor

This study shows that Agrin improves cardiac repair in pigs after myocardial infarction by reducing injury and enhancing function.

bioRxiv · Nov 25, 2019Physiology

A metabolic switch from OXPHOS to glycolysis is essential for cardiomyocyte proliferation in the regenerating heart

H. Honkoop, D. de Bakker, A. Aharonov, F. Kruse, A. Shakked, P. Nguyen, C. de Heus, L. Garric, M. Muraro, A. Shoffner, F. Tessadori, J. Peterson, W. Noort, G. Posthuma, D. Grun, , J. Bakkers

This study identifies a metabolic switch from OXPHOS to glycolysis in regenerating zebrafish hearts, showing it is essential for cardiomyocyte proliferation and heart regeneration.

bioRxiv · Dec 18, 2018Cell Biology