Author

Y. Tabach

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

E. Sharon· 2 shared E. Zisman· 2 shared I. Unterman· 2 shared A. Malina· 1 shared A. Marechal· 1 shared A. Navon· 1 shared A. Orthwein· 1 shared A. Samiei· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

E. Sharon

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cross-species identification of cancer-resistance associated genes uncovers their relevance to human cancer risk

N. U. Nair, K. Cheng, L. Naddaf, E. Sharon, L. R. Pal, P. S. Rajagopal, I. Unterman, K. Aldape, S. Hannenhalli, C.-P. Day, Y. Tabach, E. Ruppin

The paper identifies cancer-resistance associated genes across species and finds their relevance to human cancer risk through conservation analysis and functional studies.

bioRxiv · May 19, 2021 · PreprintCancer Biology

Alternative splicing of SLAMF6 in human T cells creates a co-stimulatory isoform that counteracts the inhibitory effect of the full-length receptor

E. Hajaj, E. Zisman, S. Tzaban, S. Merims, J. E. Cohen, S. Klein, S. Frankenburg, M. Sade-Feldman, Y. Tabach, K. Yizhak, A. Navon, P. Stepensky, N. Hacohen, T. Peretz, A. Veillette, , M. Lotem

This study identifies an alternative splicing event in SLAMF6 that generates a co-stimulatory isoform, which enhances T cell cytotoxicity and is associated with improved anti-tumor responses in melanoma.

bioRxiv · Aug 21, 2020 · PreprintImmunology

Conservation motifs - a novel evolutionary-based classification of proteins

H. Beer, D. Sherill-Rofe, I. Unterman, I. Bloch, M. Isseroff, D. Stupp, E. Sharon, E. Zisman, Y. Tabach

The paper classifies human proteins into seven conservation motifs based on cross-species evolutionary patterns to better describe protein evolution and function.

bioRxiv · Jan 12, 2020 · PreprintEvolutionary Biology

FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.

A. Orthwein, S. Findlay, J. Heath, V. Luo, A. Malina, Z. Li, A. Samiei, E. S. Cheyou, M. Karam, H. Bagci, D. Rahat, D. Grapton, E. G. Lavoie, C. Dove, H. Khaled, , H. Kuasne

This study identifies FAM35A as a novel REV7 effector that promotes NHEJ and restricts HR by limiting DNA end resection at DSBs.

bioRxiv · Jul 11, 2018Cancer Biology