Cancer BiologybioRxiv
Differential antitumor activity of compounds targeting the ubiquitin-proteasome machinery in gastrointestinal stromal tumor (GIST) cells
J. L. Rausch, A. A. Ali, D. M. Lee…·A. Duensing
This study evaluates second-generation proteasome inhibitors and ubiquitination regulators for their efficacy against imatinib-resistant GIST cells, finding that 20S proteasome inhibitors are effective while others show limited activity.
DOI 10.1038/s41598-020-62088-7