Author

Y. Tomari

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:protein folding & dynamics· 4 Research Focus:chromatin & epigenetic regulation· 3 Assay:proteomics· 2 Approach:biophysical modeling· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

K. Tsuboyama· 2 shared N. Izumi· 2 shared A. Arif· 1 shared A. Y. W. Lam· 1 shared C. Andersson· 1 shared D. M. Ozata· 1 shared E. Morimoto· 1 shared H. Tadakuma· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBiophysics

K. Tsuboyama

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

DNAJA2 and Hero11 mediate similar conformational extension and aggregation suppression of TDP-43

A. Y. W. Lam, K. Tsuboyama, H. Tadakuma, Y. Tomari

The paper investigates how DNAJA2 and Hero11 prevent TDP-43 aggregation by stabilizing its extended conformation using single-molecule FRET.

bioRxiv · Nov 15, 2022Biophysics

The two Gtsf paralogs in silkworms orthogonally activate their partner PIWI proteins for target cleavage

N. Izumi, K. Shoji, T. Kiuchi, S. Katsuma, Y. Tomari

This study identifies two Gtsf paralogs in silkworms that specifically activate their respective PIWI proteins for piRNA-guided target cleavage.

bioRxiv · Jun 30, 2022Biochemistry

Fusion with heat-resistant obscure (Hero) proteins have the potential to improve the molecular property of recombinant proteins

E. Morimoto, K. Tsuboyama, Y. Tomari

This study shows that fusing recombinant proteins with Hero proteins improves their solubility and stability in bacterial expression systems.

bioRxiv · Mar 3, 2022Biochemistry

Functional specialization of monocot DCL3 and DCL5 proteins through the evolution of the PAZ domain

S. Chen, W. Liu, M. Naganuma, Y. Tomari, H.-o. Iwakawa

This study identifies how monocot DCL3 and DCL5 proteins evolved distinct substrate specificities through mutations in their PAZ domains, leading to specialized siRNA production.

bioRxiv · Aug 2, 2021Plant Biology

The conserved zinc-finger protein GTSF1helps PIWI proteins achieve their full catalytic potential

A. Arif, S. Bailey, N. Izumi, T. A. Anzelon, D. M. Ozata, C. Andersson, I. Gainetdinov, I. J. MacRae, Y. Tomari, P. D. Zamore

This study identifies GTSF1 as an auxiliary protein that enhances the catalytic activity of PIWI proteins by potentiating their weak piRNA-directed RNA cleavage.

bioRxiv · May 4, 2021 · PreprintBiochemistry