The conserved zinc-finger protein GTSF1helps PIWI proteins achieve their full catalytic potential
A. Arif, S. Bailey, N. Izumi, T. A. Anzelon, D. M. Ozata, C. Andersson, I. Gainetdinov, I. J. MacRae, Y. Tomari, P. D. Zamore
This study identifies GTSF1 as an auxiliary protein that enhances the catalytic activity of PIWI proteins by potentiating their weak piRNA-directed RNA cleavage.
bioRxiv · May 4, 2021 · PreprintBiochemistry