Cancer BiologybioRxivPreprint
Cell-specific crosstalk proteomics reveals cathepsin B signaling as a driver of glioblastoma malignancy near the subventricular zone
E. S. Norton, L. A. Whaley, V. K. Jones…·H. Guerrero-Cazares
This study uses cell-specific proteomics to show that CTSB signaling from glioblastoma cells promotes malignancy by disrupting neurogenesis and inducing senescence in neural progenitor cells near the subventricular zone.
DOI 10.1101/2023.08.19.553966