PhysiologybioRxivPreprint
The gradient-based parameter optimization to determine membrane ionic current composition of human induced pluripotent stem cell-derived cardiomyocytes
H. Kohjitani, S. Koda, Y. Himeno…·T. Kimura
The paper develops a gradient-based optimization method to recover ionic current conductances from action potentials of hiPSC-CMs, showing convergence to the original parameter values.
DOI 10.1101/2022.05.16.492203