BNIP3 phosphorylation by JNK1/2 promotes mitophagy via enhancing its stability under hypoxia
Y.-L. He, S.-H. Gong, X. Cheng, M. Zhao, T. Zhao, Y. Zhao, M. Fan, L.-L. Zhu, L.-Y. Wu
This study shows that JNK1/2 phosphorylates BNIP3 under hypoxia, enhancing its stability and promoting mitophagy by increasing its binding to LC3.
bioRxiv · Aug 27, 2020Cell Biology