Cell BiologybioRxiv
BNIP3 phosphorylation by JNK1/2 promotes mitophagy via enhancing its stability under hypoxia
Y.-L. He, S.-H. Gong, X. Cheng…·L.-Y. Wu
This study shows that JNK1/2 phosphorylates BNIP3 under hypoxia, enhancing its stability and promoting mitophagy by increasing its binding to LC3.
DOI 10.1038/s41419-022-05418-z