BioengineeringbioRxivPreprint
Efficient Generation of Humanized Cloned Cattle via Embryonic Stem Cell-Mediated Dual-Round Site-Specific Editing
Zhiqiang Feng, Jing Zhang, Shenao Tao…·Jianyong Han
This study develops a method using bovine epiblast stem cells for efficient gene editing and cloning of cattle, resulting in higher birth and survival rates compared to fibroblast-based cloning.
DOI 10.64898/2025.12.20.695363