Molecular BiologyCellPeer-reviewed
mRNA 3'UTRs chaperone intrinsically disordered regions to control protein activity
Yang Luo, Yaofeng Zhong, Sudipto Basu…·Christine Mayr
The paper shows that mRNA 3'UTRs act as chaperones for intrinsically disordered regions (IDRs) to regulate protein activity by promoting IDR-IDR interactions and preventing domain folding interference.